There are no miracle cure-alls, silver bullets, or magic pills that will get you trim, fit and healthy, but after an exhaustive search and rigorous testing, The Sherpa has pinpointed a few natural health therapies that DO help and ferreted out the scams to may be shocked by what we've discovered.

Splenda and Sucralose: Avoid This Artificial Sweetener (Was Used in CHEMICAL Warfare)


Posted Monday, Jan. 30th, 2012


Would you intentionally eat a substance that when exposed to your eyes, essentially burns them and turns them blazing red?

Or how about a substance that has been used as a chemical warfare agent as far back as World War I and as recently as the Iraq war?

Well, each and every day many of you reading this do this very thing – only you have absolutely NO idea you are consuming this toxic substance.

And in fact, this very same substance has been touted as actually being healthy for you!

Get ready to be surprised.

Poison in Our Food?

In our never-ending quest to get something for nothing, food manufacturers continue to search for sugar alternatives. The most recent is touted as “tasting like sugar because it comes from sugar.” Yep, Splenda.

Splenda (known also as sucralose) is made by replacing two of the molecules from table sugar with chlorine. Yes, you read that right…it contains chlorine… the very same substance that’s been used as a chemical warfare agent and that’s routinely used to disinfect pools that our children swim in.

The resultant Splenda sugar replacement is a substance that is 600 times sweeter than sugar. And herein lies the problem.

On one side, you have Splenda advocates saying that sucralose is completely safe. On the other side you have those who say the dangers of Splenda are quite plentiful. So who’s right?

The Dangers of Splenda…

Let’s start with the history of sucralose. Like saccharine and aspartame, sucralose was also accidentally discovered…while trying to create an insecticide. Clue number one.

Clue number two is the high number of sucralose side effects.1 Those most frequently noted include:

  • Headaches
  • Skin irritation
  • Coughing
  • Runny nose
  • Heart palpitations
  • Depression and mood swings
  • Digestive issues
  • Itchy eyes

In fact, headaches may be an understatement. According to a 2006 issue of the journal Headache, researchers noted that there was “potential causal relationship” between sucralose and migraines.2 Interestingly, researchers also indicated that sucralose was approved by the FDA on April 1, 1998, taking time to note that this is April Fool’s Day!

Then there are the more serious side effects. According to a 1990 study from Food and

Chemical Toxicology, rats given sucralose had increased incidents of enlargement of the caecum (the first section of the large bowel), pelvic epithelial hyperplasia (precancerous cells of the pelvis), and renal mineralization (accumulation of mineral in the kidneys).3

In a 2008 study from Duke University and published in the Journal of Toxicology and Environmental Health, researchers found that rats given sucralose for 12 weeks were found to be more prone to obesity, less healthy intestinal bacteria, and poor absorption of prescription drugs.4

While this study does show some pretty severe Splenda-related side effects, we do have to note that the study was funded by the sugar industry, which can cast some doubt on the results.

Then there’s the study done by the manufacturers of sucralose itself that found that rats given sucralose had 40 percent shrinkage of the thymus gland, which produces T-cells and is vital for a health immune system. They also found that the sugar replacement caused enlargement of the liver and kidneys.5 This is especially problematic, given that your liver and kidneys are two of your body’s primary organs for detoxification.

Just don’t bother trying to find this study in any peer-reviewed journals. See, the findings were discovered in a pre-approval study, and for what appears to be obvious reasons, the manufacturer opted not to publish the study.

Still, one can raise the valid issues that these studies are animal studies. What about humans? Great question. Wish we could answer it for you.

The reality is, as of 2006, only six human trials have been published on sucralose, and of these, only two were published before the FDA granted approval to Splenda. Additionally, those two trials were only done on a total of 36 people.

And, of the total human studies, the longest one lasted a grand total of four days. Yep, that’s less than 100 hours.

Which then begs the question, what are the positives associated with Splenda?

Is Splenda Safe…

According to the FDA, “In determining the safety of sucralose, the FDA reviewed data from more than 100 studies in humans and animals. Many of the studies were designed to identify possible toxic effects, including carcinogenic, reproductive, and neurological effects. No such effects were found.”6

Of course, they fail to mention that only two of the studies at the time were human studies.

On the research front, several additional animal studies have found that sucralose poses no risk. In a 2000 study from Food and Chemical Toxicology, researchers fed three different dosages of sucralose to three groups of rats. They found negative side effects at all three levels.7

The group that received 1,150 times the estimated daily intake (EDI) of sucralose exhibited kidney weight and decrease thymus weights in the offspring, as well as that offspring’s offspring. All three groups (the other two took 100 times the EDI and 365 times the EDI) showed caecal enlargement (the first section of the large bowel) in both the rats that received the Splenda, as well as their offspring.

Yet, researchers didn’t mention this in their conclusion. Instead, they concluded that sucralose had no effect on glucose metabolism in sperm nor on male or female reproductive performance in rats.

What? Perhaps their argument is that the amount given was so high that it didn’t warrant comment. But they failed to determine (and continue to fail to determine) the long-term, cumulative effects of sucralose consumption.

In a human study (yes, human!), researchers tested the effects of Splenda on appetite. They conducted a randomized, single-blinded, crossover study in eight healthy subjects. Participants were studied on four different days. They drank either plain water, sucralose, a sweetened drink similar in taste to sucralose, or a modified sham-feeding of sucralose (the sucralose never hits the stomach).8

They found that drinking sucralose did not reduce insulin levels. This is good, right? But the study also found that sucralose had no effect on appetite. The reality is that the sucralose did not reduce appetite. In other words, consuming Splenda did not make the participants eat less food.

Which, of course, leads us to the biggest purported benefit of all…weight loss. Splenda is marketed as the “no calorie sweetener.” Of course, this is meant to attract those people looking to lose weight. And the fact that it is a sugar alternative is meant to appeal to diabetics and those looking to reduce their sugar intake.

Here’s the problem. There actually ARE calories in Splenda. In fact, there are 96 calories in a cup. And one little yellow packet contains four calories. Wait, what?

Yes, that’s right. According to their own Web site, the “no calorie” sweetener contains “less than 5 calories, which meets FDA’s standards for no-calorie foods.”

So four calories is actually no calories? If you can figure out how that makes sense, please let us know.

Trust Your Gut…

So where do we go from here? Trust the FDA when they say Splenda is safe? Trust the company’s own contradictory message regarding calories?

Or do you trust the studies that show a likely health risk, including a study done by the makers of the sugar replacement itself?

Once again, this is where you need to use common sense. When in doubt, go natural. Time and time again, the food industry has proven that it’s typically just a matter of time before whatever Franken-chemical they’ve created ultimately proves to be dangerous, one way or another.

So, play it safe, and opt instead for naturally sweet foods like berries and cherries to feed your sweet tooth. And if you must have a little extra kick, aim for stevia.

As we’ve indicated before, stevia has been shown to improve insulin sensitivity rather than decrease it.9 So stick with the natural and leave the chlorine in the pool.


1Kovacs, Betty. 12/13/2010.

2Patel, RM et al. Popular sweetener sucralose as a migraine trigger. Headache. 2006 Sep;46(8):1303-4.

3Lord, GH and Newberne, PM. Renal mineralization – a ubiquitous lesion in chronic rat studies. Food Chem Toxicol. 1990 Jun;28(6):449-55.

4Abou-Donia, MB et al. Splenda alters gut microflora and increases intestinal p-glycoprotein and cytochrome p-450 in male rats. J Toxicol Environ Health A. 2008;71(21):1415-29.

5New Scientist. November 23, 1991. Page 13.

6Sucralose. FDA Final Rule. United States: Food and Drug Administration.

7Kille, JW et al. Sucralose: lack of effects on sperm glycolysis and reproduction in the rat. Food Chem Toxicol. 2000;38 Suppl2:S19-29.

8Ford, HE et al. Effects of oral ingestion of sucralose on gut hormone response and appetite in healthy normal-weight subjects. Eur J Clin Nutr. 2011 Apr;65(4):508-13.

9Lailerd, N et al. Effects of stevioside on glucose transport activity in insulin-sensitive and insulin-resistant rat skeletal muscle. Metab. Clin. Exp. 2004 Jan;53(1):101-7.

Love or Hate this Article?
Either Way, Do These 2 Things Right Now!Tweet and ShareTweet and Share

  • Edward Kerr

    This information should, for obvious reasons, be common knowledge and substances of this ilk should be removed form the food supply. However, and sadly I might add, it’s not likely to ever be the case. It’s fairly obvious to me that adulterants of this sort probably have a causal relationship to the health crisis that exists in America (and the industrial countries around the world) these days.

    Thanks for doing what you can to alert people to this issue.

    Edward Kerr

    • ed is a follower

      the article is bullhit! and you believe him! minion!!!

  • Suspicious

    While you make some good points, I don’t like the scare tactics you employed by referencing chlorine – the same thing could be said for salt, NaCl.

    • Erinvalynn

      The chloride in salt is different than the chlorine in sucralose.  Chloride is natural and the compound is in an ionic bond, rendering it pretty harmless.  However, the chlorine in sucralose really is more like the chemical in your pool or what you clean your bathroom with, as it is in a covalent bond making it an organochoride and chlorocarbon, like DDT, mustard gas, and agent orange.  Remember, sucralose was originally to be an insecticide.  Sucralose is the only organocloride approved for human consumption.  Period.  It is not close to salt at all.   They are two completely different things.

      Those are the facts. But if you want to ingest an insecticide, be my guest.

      (employed by Wisdom Natural Brands, the makers of Sweetleaf Stevia)

    • Anonymous

      Different chemical compounds have different mollecular bonds – remember high-school chemistry?) Chlorine molecules may well be liberated more easily in sucralose than in salt!

  • Betty_B

    These companies should be forced to have warning labels on their packages just like cigarettes. Come on folks. Anything synthetic and not natural should make all of us think twice!

  • Anonymous

    It’s just as easy to use stevia as it is to use sucralose – just a little more expensive.
    I’m diabetic and have used sucralose since it first appeared on the shelves, and as an alternative to sugar (of course), saccharin (old negative advisories) and aspartame (newer
    negative advisories) – THINKING this was the SAFEST alternative. After reading this article, I will be buying stevia now and in the future, and tossing what’s left of my sucralose supply (just to be on the safe side).
    ADDITIONALLY, no more diet sodas with EITHER aspartame or sucralose – that completely removes sodas from my diet (shucks).
    I’ll have to read EVERY nutrition label to make sure neither are in whatever I buy.
    NEXT is a concern for drinking (iced) tea – I read that some teas (black tea, I think) contain
    microcrystalline particles that accumulate in the kidneys/bladder/both (?), which causes stones (?). It’s late and I’m not going to go looking in my files for that article tonight. That leaves WATER, milk (another no-no); fruit juice (fructose) or ganoderma coffee. Ask me about ganoderma coffee)…
    This article may well explain why recently I don’t ‘eliminate’ for 2-3 days at a time (enlarged caecum (?)), then one massive, substantial one, then another 2-3 days… (read the article)
    THAT concerns me!
    I share that ONLY because this is a health-related website. Please forgive me…
    Maybe someone can corroborate?
    I guess I’ll also have to keep a small supply of stevia in my pocket when venturing out in public, and in an emergency just use (shhhhhh) s-u-g-a-r… I NEVER thought it would come to that…
    OOPS – MUST BE clean, ‘pure’ (preferably reverse osmosis) filtered water or bottled now – public water supplies can contain trace amounts of benzene, estrogen etc.

  • Carol

    Thankyou for this.   Much info on aspartaine but never Splenda so finally I have some solid info to share with others who consume this product.

  • jessicad8695

    I’m surprised that Agave nectar isn’t being listed as a natural sweetener!

  • Shirley Gekler

    Thank you Natural Health Sherpa for doing the research that most of us are not qualified or do not have the time to do and also live our lives and earning a living for our families.  You put the information in simple language that is understandable by the majority.

    Splenda (known also as sucralose)
    is made by replacing two of the molecules from table sugar with
    chlorine. Yes, you read that right…it contains chlorine… the very same
    substance that’s been
    used as a chemical warfare agent and that’s
    routinely used to disinfect pools that our children swim in.   HOW CAN THIS MAKE SENSE TO BE CONSUMED BY OUR FAMILIES?

    Clue number two is the high number of sucralose side effects.1 Those most frequently noted

    Headaches,Skin irritation,Coughing,Runny nose,Heart palpitations,Depression and mood swings,Digestive issues, andItchy eyes.

    Now that we have been given the facts about this product and the many side effects, I cannot think of a reason to choose this product.  But we have been given the choice as to what we will do for ourselves and our families.  Now it is up to you.

  • Fgfgg

    So one should not eat hot peppers because it burns your eyes if you put it in them? Ok. Very rational and logic thinking. I stopped reading after that line.

  • bshunter

    Thanks so much for devoting 4 paragraphs to the great conspiracy that is any food marked as “no calorie”. No wonder I can’t get my waist below 50″!  I’ve been killing myself 4 calories at a time!

    • hateartificial

      EXERCISE! WALK, BIKE, RUN. Limit your consumption of food!

  • Krishna Chandra Singh Sanger

    Sodium Chloride contains more than 60% Chlorine and the chlorine is not toxic here. Please keep things in perspective and do not try to create panic by such inane observations as “Sucralose is poisonous because it contains chlorine”. Sucralose halogen containing organic compound which may be toxic. Next you would be saying common salt not only contains chlorine but the metal which produces extreme heat (burns) when it comes in contact with water and produces caustic soda (lye) which again is an extremely corrosive compound. Please confine yourself to facts that is long term health hazards of Sucralose if proven by research and not some silly and inane blabbing.

    • hateartifical

      research how the chlorine is created in each substance. Sodium chloride contains chlorine by nature. Sucralose contains it by design of a chemist! There is a BIG difference in how something is made vs how it occurs naturally in nature.

  • concerned consumer

    Huh.. and here I was wondering why every time i have something with sucralose, without even knowing it’s in there (who really looks before they drink or eat something?) and then get this nasty taste and a near burning sensation in my mouth and throat. Ugh.. more reason to stay away from that crap

  • Friedrich

    What would happen if you put any chili pepper in your eyes….or lemon juice……

    The rat study at Duke was paid for by the SUGAR lobby, hardly a credible study in anyway whatsoever.

    I am trying to find objective research to make an objective choice, but I only find websites like this one  that dont use logical reasoning or objective sources.     Just the facts please…..

    Because saccharine and aspertame are not completely safe, then sucralose is also dangerous?   that statement lacks logic…….

  • carl

    hi every one, just to tell you that there was a little erreur in the movie, they actually take out 3 groupes of H-O and replace it by 3 atomes of chlorine. After noticing the mistake in the movie, I looked at the comments and found it funny that people only watched this documentary about sucralose and think their experts on the subject when they didn’t even realize the mistake

  • Well, could somebody help me clarify this as the writer said, ” In fact, there are 96 calories in a cup ” ,. How many grams is it ?

  • 3fehtryju

    Skin irritation,
    Runny nose,
    Heart palpitations,
    Depression and mood swings,
    Digestive issues, and
    Itchy eyes.
    those are just a few, you can add nausea, stomach pains, bloating, water retaining, fevers/chills, gas/burping, throat swelling->stomach swelling each burp food/drink comes up, these symptoms dont go away after a few hours it will take 1-2 days some more
    if u consume splenda and have any of these try 1-2 days without
    gauranteed you will see a difference

    • hateartificial

      If you do get these symptoms after consuming artificial sweeteners, start taking a calcium product and a tea or other infusion (organic & natural) that contains peppermint. It will get rid of your symptoms faster and more completely.

  • MDH

    1 cup of Splenda is a lot of Splenda. What amounts are people consuming these days? I’m wondering if some of the problems people encounter with some sweeteners is due to the amounts they are consuming being too high? Or consuming too much in one sitting? Traditional sweeteners of the past (sugar and honey) will obviously give you problems if you consume too much of them. Stevia might be a natural substance, but I find it tastes quite bitter, so I don’t understand why its considered such a great sweetener. Maybe people just react to it differently according their personal body chemistry…just like all the other sweeteners, natural and manmade.

    BTW: Stick with the natural? Last time I checked, chlorine was a natural substance.

  • Adil

    BULLSHIT ARTICLE!!!! if a company is advertising that its safe for children, pregnant women, women who are nursing to consume splenda, I think its safe say that we will survive eating this sugar substitute. I’m not saying that we should believe what we read, but if a company of this magnitude is giving approvals of this nature, I don’t think their in the business of playing with peoples lives. I consume 6-7 packets of splenda a day (and that’s on the low end), I have yet to experience any of the above mentioned side effects. I have lost over 50 pounds by substituting sugar with splenda. If this moron who wrote this article can somehow prove to me that using two tablespoons of sugar with my coffee everyday, 3 times a day, that’s 6 tablespoons of sugar as opposed to 3 packets of splenda per day is going to make me live longer, then ill be convinced, and ill personally write an article condoning the use of splenda. Splenda is one of the most rigorously tested products, these clowns writing these articles need to get a life, get off there lazy asses, go to the gym, get in shape, eat sugars that naturally occur in food, and use Splenda when you want to sweeten soemthing up! read this article for the true facts about splenda

  • Pingback: sony games()

  • Pingback: nuktdbtenmknh()

  • Pingback: korepetycje angielski łódź()

  • Pingback: spy pen video camera()

  • Pingback: Marketing()

  • Pingback: stock()

  • Pingback: tree service kc()

  • C Galiardo

    I’ll let you know the next time I rub it in my eyes. You DO realize people are brushing their teeth daily with teeth whitening gels which are chlorine based and we are still alive and well. You do realize that sugar itself has the same reaction in our brains as cocaine and sends our glycemic index on a wild roller coaster ride, as well as making us FAT! Do not condemn something as dangerous if we are not using it in a comparable way. LOTS of things that are normally safe can be dangerous if misused. This product serves a lot of people very well (although I totally prefer Truvia and hope to see it in secondary product choices as well.)

  • E. Williams

    Well, I am here to tell you there ARE serious side effects to sucralose! I have suffered from ankle, leg, and hip pain from Splenda!! I went to countless doctors who could find nothing wrong with my bones. They built me braces for my legs. I couldn’t lift my legs up high enough to get out of the tub! My daughter-in-law gave me an article about the side effects of Splenda. It had a story about a person who had the same symptoms as me. He had gotten to the point that he was in a wheelchair. He quit using Splenda and the symptoms disappeared. He was now walking normal again. I decided to quit using it, too. I had been using it since it first came out. Just like him, my symptoms began to disappear. I kept thinking maybe it was because I lost about 8 pounds until I started drinking a vitamin drink that, I thought, had Truvia in it for a sweetener. It did have Truvia in it like I was told, but it was about 5 ingredients down from sucralose. My symptoms started coming back. I couldn’t figure out why. I thought about what I had changed in my diet or what I had eaten. Then I realized the only thing I changed was this vitamin drink. I looked at the ingredients and that is when I found sucralose was in it. I immediately quit the drink and my symptoms are slowly going away again. Sucralose is dangerous and people need to realize this. I have even noticed that when my husband uses Splenda, his mental capacities change. What can be done to get this off the market?? It is a poison!

  • Paul

    Please don’t try to scare people by telling them that something that contains Chlorine is bad just because Chlorine alone is a toxic substance. Everyone, I mean everyone, consumes a compound everyday that contains Chlorine atoms. Simple table/sea salt is NaCl, Sodium Chloride. Touting true facts that Chlorine was used in warfare as a means to scaring people into believing what you have to say is reckless, irresponsible, and just plain wrong.

    That being said, I do notice a burning sensation in my throat when I consume food that contains Sucralose, so I avoid it where I can. I tend to avoid all sugar substitutes, instead reducing the amount of sugar I consume. I think prefer to just have less of the real thing than replacing it with man-made substitutes.

  • dnotes

    There’s a better sweetener available, it’s called Stevia.
    When sucralose/Splenda came out I tried it as well as foods containing it such as candies with sucralose as the sweetener that clearly have the warning:’May have a laxative effect’ Well, such is the case for me if I use or eat anything with sucralose/Splenda in it along with some painful gastrointestinal discomfort and gas (an embarrassing and unwanted set of symptoms nobody wants) So while my use of it was short, just the reaction from my gut is more than enough for me to completely avoid it.
    I am so grateful that Stevia can be used in the same way (baking, cooking, mixing in hot or cold drinks) and quantities in recipes as sugar WITHOUT the unwanted symptoms of sucralose/Splenda to my insides and it is a natural source item.
    PS: The Truvia brand of Stevia is the easiest to find in grocery stores.

  • Huge Knuts

    I guess should stop eating mustard as well, since that was/is also used to make a chemical weapon.

Tags: , , , , , , , , ,

Disclaimer: The information on this site is not intended or implied to be a substitute for professional medical advice, diagnosis or treatment. All content, including text, graphics, images and information, contained on or available through this web site is for general information purposes only. Natural Health Sherpa LLC makes no representation and assumes no responsibility for the accuracy of information contained on or available through this web site, and such information is subject to change without notice. You are encouraged to confirm any information obtained from or through this web site with other sources, and review all information regarding any medical condition or treatment with your physician.